Sympathetic Inhibition of Accommodation after Sustained Nearwork in Subjects with Myopia and Emmetropia

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Sympathetic inhibition of accommodation after sustained nearwork in subjects with myopia and emmetropia.

PURPOSE The purposes of the present study were to assess the effect of a sympathetic inhibitory pharmacologic agent, timolol maleate, on the magnitude of nearwork-induced transient myopia (NITM) and its decay in different refractive groups for an extended near task duration and to determine the proportion of the young adult population manifesting effective sympathetic access under naturalistic ...

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The Progression of Nearwork Myopia

The purpose of this letter is to present a simplified mathematical model of progressive myopia. A proposed hypothesis for refractive error development of the human eye requires that there is an optical signal related to the amount of refractive error which would in turn correct the refractive error of the eye. A specific first-order feedback system, defined by the transfer function F (s) = 1 / ...

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The effect of topical β-adrenoceptor antagonists on accommodation in emmetropia and myopia

Using topical instillation of non-selective and selective beta-adrenoceptor antagonists we examine the proposal that a deficit in inhibitory sympathetic innervation of ciliary smooth muscle may be a specific precursor to the onset and development of late-onset myopia (LOM). Post-task accommodative hysteresis, a possible consequence of such a deficit, was assessed by measuring the time-course of...

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ژورنال

عنوان ژورنال: Investigative Opthalmology & Visual Science

سال: 2009

ISSN: 1552-5783

DOI: 10.1167/iovs.08-1762